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Artoindonesianin-E a New Flavanone Derivative from Artocarpus Champeden

Euis Holisotan Hakim, Asep Aripin, Sjamsul Arifin Achmad, Norio Aimi, Mariko Kitajima, Lukman Makmur, Didin Mujahidin, Yana Maolana Syah & Hiromitsu Takayama


Abstract. A new flavanone derivative, 5,7-dihydroxy-2',4',6'-trimethoxyflavanone named artoindonesianin-E (1) had been isolated for the first time, together with artocarpin (2) and heteroflavanone-A (3) from benzene extract of the tree bark of Artocarpus champeden Spreng. (Moraceae), a species endemic to Indonesia and locally known as Cempedak. The structure of this compound was elucidated based on physical and spectroscopic data (MS, 1H and 13C NMR).

Keywords: Artocarpin; Artocarpus champeden Spreng.; artoindonesianin-E; Cempedak; flavanone; heteroflavanone; Moraceae

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