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Ilmu Kimia Tumbuhan Lauraceae Indonesia: X. Alkaloid Benzilisokuinolin Dari Litsea cassiaefolia

Euis Holisotan Hakim, Sjamsul Arifin Achmad, Buchari & Sidharta Pramutadi

 


Abstract. The first chemical study on Litsea cassiaefolia had been carried out in our laboratory. In this investigation, by combination of partition chromatography and common separation methods, three alkaloids had been isolated, namely dicentrine (I), dehydrodicentrine (II), and dicentrinone (III), which belong to benzylisoquinoline alkaloids of the types aporphine, dehydroaporphine, and oxoaporphine, respectively. The characterization of the alkaloids had been based upon the UV, 1H-NMR, 13C-NMR and mass spectroscopic evidence. Among these compounds, dicentrine (I) is the major alkaloid which may be isolated in relatively higher yield, thus, the biological property of this compound is being further investigated. Finding the alkaloids in this plant is beneficial as a basis for chemotaxonomy.

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