Etude Par Fragmentographie de Masse de la Cinetique Sanguine D'un Anti-Inflammatoire DU F-1594
A. Hanafiah WS & Badruzzaman S.
Abstract. The determination of p-biphenyl-4, oxo-4, methyl-2-butyric acid (F-1594) as an antiinflammatory agent in the human plasma by using gas chromatography-mass spectrometry is described. Quantitation was achieved after extraction from the plasma, F 1594 and p-biphenyl 4-chloro 2’-acetic acid as an internal standard, separated by gas chromatography with the capillary column and analysed by mass fragmentography. This process requires only a very little sample and it enables the detection of very low concentration.
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